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|Pronunciation||/ eɪ ˈ s aɪ k l oʊ v ɪər /|
|Trade names||Zovirax, others |
|License data||US FDA: Acyclovir|
|Pregnancy category||AU: B3 US: B (No risk in non-human studies)|
|Routes of administration||Intravenous, by mouth, topical (including eye ointment)|
|ATC code||J05AB01 ( WHO ) D06BB03 ( WHO ) S01AD03 ( WHO )|
|Legal status||AU: S4 (Prescription only) for tablet and injection. Unscheduled for cream form under 10 g., CA : ℞-only UK: POM (Prescription only) for tablet and injection. GSL (OTC) for cream form under 2 g., US: ℞-only|
|Bioavailability||15–20% (by mouth) |
|Protein binding||9–33% |
|Elimination half-life||2–4 hours|
|Excretion||Kidney (62–90% as unchanged drug)|
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Results from previous studies of carcinogenesis, mutagenesis and fertility for acyclovir and hydrocortisone are not included in the order generic acyclovir prescribing information for XERESE due to the minimal exposures that result from dermal application.IV to PO programs are commonly driven by the pharmacy service and are endorsed by multiple organizations as good a measure for antibiotic stewardship. As new healthcare practitioners enter the workforce, current providers engage in antibiotic stewardship, and institutions seek to adhere to good antimicrobial stewardship practices, changing from IV to PO antibiotics will continue to be an important topic.
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