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Dapoxetine
Clinical data
Trade namesPriligy, others (see below)
AHFS/Drugs.comInternational Drug Names
Routes of administrationOral (tablets)
ATC codeG04BX14 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability15–76% (mean 42%), T max = 1–1.3 hours
Protein binding>99%
MetabolismLiver (CYP2D6, CYP3A4), kidney (FMO1)
MetabolitesDapoxetine- N -oxide, desmethyldapoxetine, didesmethyldapoxetine
Elimination half-life1.5–1.6 h
ExcretionKidneys [1]

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Simulated CYP3A4 inhibitors. Begging of ketoconazole 200 mg priligy in malaysia twice for 7 days priligy in malaysia the Cmax and AUCinf of dapoxetine 60 mg every dose by 35 and 99 primarily. Considering the acute of both unbound dapoxetine and desmethyldapoxetine, the Cmax of the united kingdom may be detected by little 25 and the AUC of the future fraction may be carried if taken with trying CYP3A4 inhibitors.

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    K If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or our pharmacist before taking this product.This action stops the ejaculation expulsion reflex from reaching the brain too quickly, increasing the time it takes to ejaculate and improving control over the ejaculation.

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    Patients must understand that dapoxetine helps them to control ejaculation only temporarily and that PE is controllable and not curable. Other cited reasons for discontinuation were priligy in malaysia effects like nausea and dizziness 12% and poor efficacy 10% About 6% of the men sought other treatment options and for 18% the reason for stopping dapoxetine was unknown.see While you are taking PRILIGY and Side Effects PRILIGY contains the priligy in malaysia ingredient dapoxetine and is a type of drug called a selective serotonin reuptake inhibitor SSRI and it is also known as a urological medicine.

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    Kilinc MF, Aydogmus Y, Yildiz Y, Doluoglu OG. Impact of priligy in malaysia activity on patient self-reported outcomes of lifelong premature ejaculation patients: Results of a prospective, randomised, sham-controlled trial.Eur Urol.

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    Owever, it is presumed that dapoxetine works by inhibiting serotonin transporter and priligy in malaysia increasing serotonin's action at pre and postsynaptic receptors 18 Human ejaculation is regulated by various areas in the central nervous system CNS 19 The ejaculatory pathway originates from spinal reflex at the thoracolumbar and lumbosacral level of spinal cord activated by stimuli from male genital.Pu C, Yang L, Liu L, Yuan H, Wei Q, Han P.

    Topical anesthetic agents for premature ejaculation: a systematic review and meta-analysis. Urology.

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