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|Trade names||Remeron, others|
|License data||US FDA: Mirtazapine|
|Pregnancy category||AU: B3 US: C (Risk not ruled out)|
|Routes of administration||By mouth (tablets)|
|ATC code||N06AX11 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Bioavailability||50%    |
|Protein binding||85%    |
|Metabolism||Liver (CYP1A2, CYP2D6, CYP3A4)     |
|Metabolites||Desmethylmirtazapine (contributes 3–10% of activity) |
|Elimination half-life||20–40 hours    |
|Excretion||Urine: 75%  Feces: 15%    |
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U TGA pregnancy category: B3US FDA pregnancy category: CComments: Use of adequate methods of contraception should be encouraged.Medline. Harris EC, Barraclough B. Suicide as an outcome for mental disorders.
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Patients with a history of mania/hypomania should be closely monitored.emeron is an effective antidepressant; however, its use may be limited by its prominent sedative effects.
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