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|Trade names||Nicorette, Nicotrol|
|Pregnancy category||AU: D US: D (Evidence of risk)|
|Dependence liability||Physical: low–moderate Psychological: moderate–high  |
|Addiction liability||High |
|Routes of administration||Inhalation; insufflation; oral – buccal, sublingual, and ingestion; transdermal; rectal|
|ATC code||N07BA01 ( WHO ) QP53AX13 ( WHO )|
|Legal status||US: OTC and ℞ (prescription) |
|Metabolism||Primarily hepatic: CYP2A6, CYP2B6, FMO3, others|
|Elimination half-life||1-2 hours; 20 hours active metabolite|
|Excretion||Renal, urine pH-dependent;  10–20% (gum), 30% (inhaled); 10–30% (intranasal)|
|NFPA 704 fire diamond|
|1 4 0 The fire diamond hazard sign for nicotine. |
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