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The parent drug forms a single N-desethyl metabolite, which inhibits CA-II less potently than the parent drug but also inhibits CA-I.A drug patent is bought timoptic eye drops by the U. Patent and Trademark Office and buys timoptic eye drops exclusive legal right to the patent holder to protect the proprietary chemical formulation.

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TIMOPTIC-XE timolol maleate ophthalmic gel forming solution 0.Beta-adrenergic receptor blockade reduces cardiac output in both healthy subjects and patients with heart disease. In patients with severe impairment of myocardial function beta-adrenergic receptor inhibitors may inhibit the stimulatory effect of the sympathetic nervous system necessary to maintain adequate cardiac function.

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2.Timolol ophthalmic solution also is contraindicated in patients with known hypersensitivity to the drug or any ingredient in the formulation.

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Following prolonged therapy with topical timolol, the effect in reducing IOP is generally well maintained, but tolerance has been reported in some patients. In one long-term buy timoptic in patients receiving timolol for at least 3 years, the reduction in buy timoptic IOP was maintained following initial stabilization with the drug.In double-blind studies in patients with open-angle glaucoma, usual doses of timolol have been found to be at least as effective as therapeutic doses of pilocarpine in reducing elevated IOP without the miosis, ocular irritation, and blurred vision associated with pilocarpine therapy.

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Overdosage has been reported buy timoptic eye drops timolol maleate tablets.If timolol is used to reduce IOP in patients with angle-closure glaucoma, the drug should not be used alone but rather in combination with a topical miotic since timolol has little or no effect on pupil size.

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