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Clinical data
Pronunciation/ eɪ ˈ s aɪ k l oʊ v ɪər /
Trade namesZovirax, others [1]
License dataUS   FDA: Acyclovir
Pregnancy categoryAU: B3 US: B (No risk in non-human studies)
Routes of administrationIntravenous, by mouth, topical (including eye ointment)
ATC codeJ05AB01 ( WHO ) D06BB03 ( WHO ) S01AD03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) for tablet and injection. Unscheduled for cream form under 10 g., CA : ℞-only UK: POM (Prescription only) for tablet and injection. GSL (OTC) for cream form under 2 g., US: ℞-only
Pharmacokinetic data
Bioavailability15–20% (by mouth) [2]
Protein binding9–33% [2]
Elimination half-life2–4 hours
ExcretionKidney (62–90% as unchanged drug)

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Zovirax information
Drug name Zovirax
Zovirax product namesacicvir, acifur, acyclovirum, avirax, cicloferon, epsin, firex, ocuvir, soviclor, virovir, zirconia
Active substancesacyclovir
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    The Prevention of Opportunistic Infections Working Group of the US Public Health Service and the Infectious Diseases Society of America USPHS/IDSA has established guidelines for the prevention of opportunistic infections in HIV-infected individuals that include recommendations concerning prevention of exposure to opportunistic pathogens, prevention of first disease episodes, and prevention of disease recurrence.

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