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Ondansetron
Clinical data
Trade namesZofran, Ondisolv, others
AHFS/Drugs.comMonograph
MedlinePlusa601209
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth, rectal, IV, IM
ATC codeA04AA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability~60%
Protein binding70–76%
MetabolismLiver (CYP3A4, CYP1A2, CYP2D6)
Elimination half-life5.7 hours
ExcretionKidney

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Oderately nauseating chemotherapy: Take 8 mg tablet 30 minutes prior to chemotherapy and repeat in 8 hours, then 8 mg every 12 hours for 1 to 2 days after chemotherapy. adiation-induced nausea and vomiting: Take 8 mg orally 1 to 2 hours prior to radiation and every 8 hours after first dose, as needed.I told him I'd spot him by standing next to him.

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This may happen as a result of the following: Javascript is disabled or blocked by an extension ad blockers for example Your what doe ondansetron pill look like does not support cookies Please make sure that Javascript and cookies are enabled on your browser and that you are not blocking them from loading. Questions: m Reference ID: #1.Dizziness has been reported in 7% of patients receiving ondansetron orally in recommended dosages for prevention of postoperative nausea and vomiting in controlled clinical trials.

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Opyright 1997-2020 BabyCenter, LLC. All rights reserved.Most reports have been associated with concomitant use of serotonergic drugs e. selective serotonin reuptake inhibitors SSRIs serotonin and norepinephrine reuptake inhibitors SNRIs monoamine oxidase inhibitors, mirtazapine, fentanyl, lithium, tramadol, and intravenous methylene blue Some of the reported cases were fatal.

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I have tried it for both my everyday nausea and my migraine nausea, but I would still throw up.Treatment response was based on the total number of emetic episodes over the 3-day trial period. See Table 8 for the details of the dosage regimens studied and results of this trial.

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Circulating drug also distributes into erythrocytes. Ondansetron is extensively metabolized in humans, with approximately 5% of a radiolabeled ondansetron pill identification recovered as the parent compound from the urine.In patients with severe hepatic impairment Child-Pugh2 score of 10 or greater clearance is reduced and apparent volume of distribution is increased with a resultant increase in plasma half-life.

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