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Clinical data
Trade namesDiflucan, Celozole, others
License dataUS   FDA: fluconazole
Pregnancy categoryAU: D US: C (Risk not ruled out) (low dose)
Routes of administrationby mouth, IV, topical
ATC codeD01AC15 ( WHO ) J02AC01 ( WHO )
Legal status
Legal statusAU: S3 (Pharmacist only) / S4, UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability>90% (oral)
Protein binding11–12%
Metabolismliver 11%
Elimination half-life30 hours (range 20-50 hours)
Excretionkidney 61-88%
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Medline. Singh A, Masih A, Khurana A, Singh PK, Gupta M, Hagen F, et al. Half terbinafine construction in Trichophyton interdigitale teas in Delhi, India debtor morsels in the squalene epoxidase chris. Polymorphisms. 2018 Jul. 7-484.

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PMC apostolic fermentation PubMed CrossRef Fluconazole capsule Channel Cuenca-Estrella M. 2010 Antif ngicos en el tratamiento de las infecciones document micas: importancia del mecanismo de acci n, espectro de actividad y resistencias. ubMed Google School Cui J. Ren B. Cause Y. Dai H. Zhang L. 2015 Synergistic bates of antifungals and for-virulence agents to do against Candida albicans.

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This is especially concerning because echinocandins are the first-line treatment for Candida glabrata, which already has high levels of resistance to fluconazole.: Invasive Candidiasis Statistics - CDC

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Abdulah R, Suwandiman TF, Handayani N, Destiani DP, Suwantika AA, Barliana MI, Lestari K. Ther Clin Risk Manag. 2017 Jul. 925. Irregular treatment with topical agents and oral antifungals including ketoconazole and fluconazole, first for 6 months and then for 1 year had led to no  ... An open-label, comparative study of the efficacy and safety of Diflucan 2 to 3 mg/kg/day and oral nystatin.

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UpToDate. Waltham, MA: UpToDate.5- nortriptyline and/or S-amitriptyline may be measured at initiation of the combination therapy and after one week. Dosage of amitriptyline/nortriptyline should be adjusted, if necessary.

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A published survey of 96 breastfeeding women who were treated with fluconazole 150 mg every other day average of 7. capsulesrange 1 to 29 capsules for lactation-associated candida of the breasts reported no serious adverse reactions in infants.ho.

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Of patients due to adverse clinical events and in 1. of patients due to laboratory test abnormalities.wavy ribs, cleft palate, abnormal craniofacial ossification These adverse effects in rats may be attributed to a species-specific effect of fluconazole on estrogen synthesis since lowered estrogen 200 mg fluconazole known to cause effects on 200 mg fluconazole, organogenesis, and parturition.

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An increase in the dose of fluconazole should be considered in combination 200 mg fluconazole. Concomitant use of the following other medicinal products cannot be recommended Amiodarone: concomitant administration of fluconazole with amiodarone may increase QT prolongation.The dizziness was freaking horrible.

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See CLINICAL PHARMACOLOGY: Drug Interaction Studies. Terfenadine: Because of the fluconazole dosage for yeast infection male of serious cardiac dysrhythmias secondary to prolongation of the QTc interval in patients receiving azole antifungals in conjunction with terfenadine, interaction studies have been performed.Read this information carefully before you take Fluconazole Tablets, USP.

Ask your doctor or pharmacist if you do not understand any of this information or if you want to know more about Fluconazole Tablets, USP. Fluconazole Tablets, USP is a tablet you swallow to treat vaginal yeast infections caused by a yeast called Candida.

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For the treatment of esophageal candidiasis in HIV-infected infants and children, CDC, NIH, and IDSA recommend that fluconazole be given in a dosage of 6-12 mg/kg up to 600 mg once daily for a minimum of 3 weeks and for at least 2 weeks after symptoms resolve. If long-term suppressive or maintenance therapy secondary prophylaxis fluconazole 200 mg tablet fluconazole is used in HIV-infected infants and children with frequent or severe recurrences of esophageal candidiasis, a dosage of 3-6 mg/kg up to 200 mg once daily is recommended.The combination may be used while taking increased consideration to the risk of increased serum bilirubin and serum creatinine.

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To avoid a possible serious reaction, do NOT take fluconazole if you are taking erythromycin, astemizole, pimozide, quinidine, and cisapride Propulsid since it can cause changes in heartbeat in some people if taken with fluconazole.Dis. 8: 03-535. arkins, M. D. D. M. Sabuda, S. Elsayed, and K. B. Laupland.

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Siga cuidadosamente las instrucciones de su m dico. Fluconazole oral se toma por la boca.1PubMed CrossRef Google Scholar Silva A. P. Miranda I. M. Guida A. Synnott J. Rocha R. Silva R. et al.

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See PRECAUTIONS. Midazolam: The effect of fluconazole on 200 mg fluconazole pharmacokinetics and pharmacodynamics of midazolam was examined in a randomized, cross-over study in 12 volunteers.800 mg daily may be considered for some infections and especially for meningeal disease In general, the recommended duration of therapy for candidemia 200 mg fluconazole for 2 weeks after first negative blood culture result and resolution of signs and symptoms attributable to candidemia.

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