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Tell your doctor if you are breastfeeding or plan to breastfeed. Tacrolimus has been detected in human breast milk.Not all possible drug interactions are listed here. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect.

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Epub 2016 Feb 13.Ajay K Singh, MB, MRCP, MBA Associate Professor of Medicine, Harvard Medical School; Director of Dialysis, Renal Division, Brigham and Women's Hospital; Director, Brigham/Falkner Dialysis Unit, Faulkner HospitalDisclosure: Nothing to disclose.

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In normal skin, multiple lamellar sheets of hydrophobic lipids surround the nucleate corneocytes, providing a waterproofing shield that retards movement of click and water-soluble substances across the stratum corneum. These lipids are delivered to the stratum corneum interstices by a secretory organelle, the epidermal lamellar body.All female patients presented with characteristic porcelain-white atrophic scarring in a figure-8 pattern around the vulva and anus and associated with hemorrhages and erosions Figure 1, A In addition, patient 3 had a perineal protrusion, an unusual manifestation of lichen sclerosus recently described.

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Eichenfield LF, Tom WL, Berger TG, Krol A, Paller AS, Schwarzenberger K, Bergman JN, Chamlin SL, Cohen DE, Cooper KD, Cordoro KM, Davis DM, Feldman SR, Hanifin JM, Margolis DJ, Silverman RA, Simpson EL, Williams HC, Elmets CA, Block J, Harrod CG, Smith Begolka W, Sidbury R. J Am Acad Dermatol. 2014 Jul; 1 116-32.Concentrations of TAC, mycophenolic acid MPA and metabolites were analyzed and relevant genotypes were determined from 32 patients.

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Therefore, monitoring of whole blood trough concentrations is recommended to assist in the clinical evaluation of toxicity and efficacy failure.ITT analysis was done, but the method was not describedSelective reporting reporting bias ow riskAll relevant outcomes were describedOther biasLow riskThis trial was free of other biasMethodsRCT randomised, double blind, multicentre, comparative study articipantsPaediatric patients 2 to 15 years with moderate to severe AD Rajka and Langeland criteria Rajka 1989 InterventionsTacrolimus ointment 0.

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